Varaico: Literature-Extracted Genetic Variants

WT1

1,404 papers

RefSeq Summary

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the norm...

Pfam Domains

WT1aa 1–321UCSCWilm's tumour protein

WT1aa 3–169UCSCWilm's tumour protein

WT1aa 74–377UCSCWilm's tumour protein

zf-C2H2aa 201–225UCSCZinc finger, C2H2 type

zf-C2H2aa 231–253UCSCZinc finger, C2H2 type

zf-C2H2aa 262–286UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

WT1 transcription factor

HGNC Previous Symbol

GUD

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_024426.6

p.L383_S386insFs

c.1148_1157dup10

Surrounding Variants

1 paper

NM_024426.6

p.S386insFs

c.1157dupC

2 papers

NM_024426.6

p.R385_S386insFs

c.1153_1157dup5

1 paper

NM_024426.6

p.S386insFs

c.1157_1158ins11

3 papers

NM_024426.6

p.S386fs

c.1156_1157fs

1 paper

NM_024426.6

p.S386_A387insFs

c.1158_1159ins17

1 paper

NM_024426.6

p.S386_A387insFs

c.1158_1159insA

1 paper

NM_000378.6

p.S369S

c.1107G>A

1 paper

NM_024426.6

p.S386delFs

c.1157delG

1 paper

NM_024426.6

p.A387S

c.1159G>T

1 paper

NM_024426.6

p.A387insFs

c.1159_1160ins4

9 papers

NM_024426.6

p.S386*

c.1157C>A

6 papers

NM_024426.6

p.A387fs

c.1159_1160fs