Varaico: Literature-Extracted Genetic Variants

WT1

1,404 papers

RefSeq Summary

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the norm...

Pfam Domains

WT1aa 1–321UCSCWilm's tumour protein

WT1aa 3–169UCSCWilm's tumour protein

WT1aa 74–377UCSCWilm's tumour protein

zf-C2H2aa 201–225UCSCZinc finger, C2H2 type

zf-C2H2aa 231–253UCSCZinc finger, C2H2 type

zf-C2H2aa 262–286UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

WT1 transcription factor

HGNC Previous Symbol

GUD

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

9 papers

NM_024426.6

p.S386*

c.1157C>A

Surrounding Variants

1 paper

NM_024426.6

p.S386insFs

c.1156_1157ins11

1 paper

NM_024426.6

p.S386insFs

c.1156_1157ins5

1 paper

NM_024426.6

p.S386ins2

c.1156_1157ins6

3 papers

NM_024426.6

p.R385insFs

c.1155dupG

1 paper

NM_024426.6

p.R385insFs

c.1154_1155dupGG

1 paper

NM_024426.6

p.V384_R385insFs

c.1152_1155dup4

1 paper

NM_000378.6

p.R368delFs

c.1104delC

1 paper

NM_024426.6

p.V379_R385del7

c.1135_1154del21

1 paper

NM_024426.6

p.V376_R385del10

c.1126_1154del30

1 paper

NM_024426.6

p.S386insFs

c.1157dupC

2 papers

NM_024426.6

p.R385_S386insFs

c.1153_1157dup5

2 papers

NM_024426.6

p.L383_S386insFs

c.1148_1157dup10