Varaico: Literature-Extracted Genetic Variants

WT1

1,404 papers

RefSeq Summary

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the norm...

Pfam Domains

WT1aa 1–321UCSCWilm's tumour protein

WT1aa 3–169UCSCWilm's tumour protein

WT1aa 74–377UCSCWilm's tumour protein

zf-C2H2aa 201–225UCSCZinc finger, C2H2 type

zf-C2H2aa 231–253UCSCZinc finger, C2H2 type

zf-C2H2aa 262–286UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

WT1 transcription factor

HGNC Previous Symbol

GUD

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_024426.6

p.L383insFs

c.1148_1149ins4

Surrounding Variants

1 paper

NM_024426.6

p.P381_L383insFs

c.1143_1147dup5

1 paper

NM_024426.6

p.T382_L383insFs

c.1144_1148dup5

1 paper

NM_024426.6

p.L383_V384insFs

c.1149_1150ins13

2 papers

NM_024426.6

p.L383fs

c.1147_1148fs

2 papers

NM_024426.6

p.P381_T382insFs

c.1141_1144dup4

1 paper

NM_024426.6

p.P381_T382delFs

c.1141_1144del4

1 paper

NM_024426.6

p.V384I

c.1150G>A

1 paper

NM_024426.6

p.V384fs

c.1150_1151fs

1 paper

NM_024426.6

p.P377_V384delFs

c.1129_1150del22

1 paper

NM_024426.6

p.T382insFs

c.1145_1146ins4

1 paper

NM_024426.6

p.T382insFs

c.1145_1146ins4

3 papers

NM_024426.6

p.G378_P381insFs

c.1133_1142dup10