Varaico: Literature-Extracted Genetic Variants

WT1

1,404 papers

RefSeq Summary

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the norm...

Pfam Domains

WT1aa 1–321UCSCWilm's tumour protein

WT1aa 3–169UCSCWilm's tumour protein

WT1aa 74–377UCSCWilm's tumour protein

zf-C2H2aa 201–225UCSCZinc finger, C2H2 type

zf-C2H2aa 231–253UCSCZinc finger, C2H2 type

zf-C2H2aa 262–286UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

WT1 transcription factor

HGNC Previous Symbol

GUD

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

14 papers

NM_024426.6

p.P381Q

c.1142C>A

Surrounding Variants

1 paper

NM_024426.6

p.P381Fs

c.1142delinsGTFs

1 paper

NM_024426.6

p.P381insFs

c.1142_1143insT

1 paper

NM_024426.6

p.P381insFs

c.1142_1143ins4

1 paper

NM_024426.6

p.P381insFs

c.1142_1143ins10

1 paper

NM_024426.6

p.A380_P381insFs

c.1140_1141ins4

3 papers

NM_024426.6

p.V379_P381insFs

c.1137_1141dup5

2 papers

NM_024426.6

p.P377_P381insFs

c.1131_1141dup11

1 paper

NM_024426.6

p.P381insFs

c.1142_1143insAA

9 papers

NM_024426.6

p.P381insFs

c.1142dupC

1 paper

NM_024426.6

p.A380insFs

c.1139_1140dupCC

1 paper

NM_024426.6

p.V379_P381insFs

c.1136_1142dup7

1 paper

NM_024426.6

p.P377_P381insFs

c.1130_1142dup13