Varaico: Literature-Extracted Genetic Variants

WT1

1,404 papers

RefSeq Summary

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the norm...

Pfam Domains

WT1aa 1–321UCSCWilm's tumour protein

WT1aa 3–169UCSCWilm's tumour protein

WT1aa 74–377UCSCWilm's tumour protein

zf-C2H2aa 201–225UCSCZinc finger, C2H2 type

zf-C2H2aa 231–253UCSCZinc finger, C2H2 type

zf-C2H2aa 262–286UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

WT1 transcription factor

HGNC Previous Symbol

GUD

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_024426.6

p.A380Fs

c.1138delinsGTFs

Surrounding Variants

1 paper

NM_024426.6

p.A380insFs

c.1139_1140ins4

2 papers

NM_024426.6

p.A380Fs

c.1138delinsGGFs

1 paper

NM_024426.6

p.A380Fs

c.1138delinsGGGFs

1 paper

NM_024426.6

p.P377_A380insFs

c.1131_1138dup8

1 paper

NM_024426.6

p.A380insFs

c.1139_1140ins8

1 paper

NM_024426.6

p.A380Fs

c.1138delinsGAFs

1 paper

NM_024426.6

p.A380delFs

c.1138delC

1 paper

NM_024426.6

p.G378_V379del1

c.1134_1136delACT

3 papers

NM_024426.6

p.A380insFs

c.1138_1139insT

1 paper

NM_024426.6

p.A380insFs

c.1138_1139ins8

4 papers

NM_024426.6

p.V379insFs

c.1137dupA

1 paper

NM_024426.6

p.A380insFs

c.1138_1139ins4