Varaico: Literature-Extracted Genetic Variants

WT1

1,404 papers

RefSeq Summary

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the norm...

Pfam Domains

WT1aa 1–321UCSCWilm's tumour protein

WT1aa 3–169UCSCWilm's tumour protein

WT1aa 74–377UCSCWilm's tumour protein

zf-C2H2aa 201–225UCSCZinc finger, C2H2 type

zf-C2H2aa 231–253UCSCZinc finger, C2H2 type

zf-C2H2aa 262–286UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

WT1 transcription factor

HGNC Previous Symbol

GUD

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_024426.6

p.V376delFs

c.1127_1128delCA

Surrounding Variants

1 paper

NM_024426.6

p.P377fs

c.1129_1130fs

4 papers

NM_024426.6

p.P377S

c.1129C>T

1 paper

NM_024426.6

p.P377insFs

c.1129_1130ins8

1 paper

NM_024426.6

p.V376insFs

c.1128dupG

3 papers

NM_024426.6

p.V376insFs

c.1127_1128ins7

1 paper

NM_024426.6

p.V376_P377insFs

c.1128_1129ins5

1 paper

NM_024426.6

p.P377insFs

c.1129_1130ins4

2 papers

NM_000378.6

p.V359insFs

c.1076_1077insT

NM_024426.6

p.V376insFs

c.1127_1128insT

1 paper

NM_024426.6

p.V376insFs

c.1127_1128insTT

1 paper

NM_024426.6

p.V376_P377insFs

c.1128_1129insTC

1 paper

NM_024426.6

p.V376fs

c.1126_1127fs

1 paper

NM_024426.6

p.P377insFs

c.1129_1130ins11