Varaico: Literature-Extracted Genetic Variants

WT1

1,404 papers

RefSeq Summary

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the norm...

Pfam Domains

WT1aa 1–321UCSCWilm's tumour protein

WT1aa 3–169UCSCWilm's tumour protein

WT1aa 74–377UCSCWilm's tumour protein

zf-C2H2aa 201–225UCSCZinc finger, C2H2 type

zf-C2H2aa 231–253UCSCZinc finger, C2H2 type

zf-C2H2aa 262–286UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

WT1 transcription factor

HGNC Previous Symbol

GUD

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

4 papers

NM_024426.6

p.R375fs

c.1123_1124fs

NM_001198552.2

p.R141fs

c.421_422fs

Surrounding Variants

1 paper

NM_024426.6

p.R375insFs

c.1124dupG

1 paper

NM_024426.6

p.R375Fs

c.1124delinsTGCCCCCCTFs

3 papers

NM_024426.6

p.R375insFs

c.1125dupT

2 papers

NM_024426.6

p.V376insFs

c.1126_1127insCG

3 papers

NM_024426.6

p.R375insFs

c.1124_1125insC

2 papers

NM_024426.6

p.R375P

c.1124G>C

1 paper

NM_024426.6

p.R375Fs

c.1124delinsCCFs

1 paper

NM_024426.6

p.R375H

c.1124G>A

5 papers

NM_024426.6

p.V376fs

c.1126_1127fs

1 paper

NM_024426.6

p.R374_R375Fs

c.1122_1124delinsGCCCFs

1 paper

NM_024426.6

p.R375_V376insFs

c.1123_1126dup4

1 paper

NM_024426.6

p.V376insFs

c.1127_1128insAC