Varaico: Literature-Extracted Genetic Variants

WT1

1,404 papers

RefSeq Summary

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the norm...

Pfam Domains

WT1aa 1–321UCSCWilm's tumour protein

WT1aa 3–169UCSCWilm's tumour protein

WT1aa 74–377UCSCWilm's tumour protein

zf-C2H2aa 201–225UCSCZinc finger, C2H2 type

zf-C2H2aa 231–253UCSCZinc finger, C2H2 type

zf-C2H2aa 262–286UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

WT1 transcription factor

HGNC Previous Symbol

GUD

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_024426.6

p.V373delFs

c.1117delC

Surrounding Variants

1 paper

NM_024426.6

p.D372fs

c.1114_1115fs

7 papers

NM_024426.6

p.R374*

c.1120C>T

1 paper

NM_024426.6

p.R374Fs

c.1120delinsGGFs

2 papers

NM_024426.6

p.V373_R374insFs

c.1119_1120insGG

1 paper

NM_024426.6

p.R374_R375ins4

c.1120_1124ins12

1 paper

NM_024426.6

p.R374insFs

c.1120_1121insA

4 papers

NM_024426.6

p.R374fs

c.1120_1121fs

1 paper

NM_024426.6

p.R374ins4

c.1121_1122ins12

1 paper

NM_024426.6

p.R374Q

c.1121G>A

1 paper

NM_024426.6

p.D372delFs

c.1114delC

7 papers

NM_024426.6

p.R374R

c.1122A>G

1 paper

NM_024426.6

p.R374insFs

c.1121dupG