Varaico: Literature-Extracted Genetic Variants

WT1

1,404 papers

RefSeq Summary

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the norm...

Pfam Domains

WT1aa 1–321UCSCWilm's tumour protein

WT1aa 3–169UCSCWilm's tumour protein

WT1aa 74–377UCSCWilm's tumour protein

zf-C2H2aa 201–225UCSCZinc finger, C2H2 type

zf-C2H2aa 231–253UCSCZinc finger, C2H2 type

zf-C2H2aa 262–286UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

WT1 transcription factor

HGNC Previous Symbol

GUD

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_024426.6

p.L316insFs

c.946_947insAA

Surrounding Variants

1 paper

NM_024426.6

p.N315delFs

c.943delT

1 paper

NM_024426.6

p.L316_G317insFs

c.948_949insG

1 paper

NM_024426.6

p.N315insFs

c.944_945insCG

1 paper

NM_024426.6

p.G317insFs

c.949_950ins5

1 paper

NM_024426.6

p.M314fs

c.940_941fs

1 paper

NM_024426.6

p.G317E

c.950G>A

1 paper

NM_024426.6

p.Q313_M314insFs

c.937_940dup4

1 paper

NM_024426.6

p.A318P

c.952G>C

1 paper

NM_024426.6

p.Q313_G317del5

c.937_950del15

1 paper

NM_024426.6

p.M314insFs

c.940_941ins4

1 paper

NM_024426.6

p.Q313_M314ins1

c.939_940insAAG

1 paper

NM_024426.6

p.T310_Q313insFs

c.929_938dup10