Varaico: Literature-Extracted Genetic Variants

WT1

1,404 papers

RefSeq Summary

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the norm...

Pfam Domains

WT1aa 1–321UCSCWilm's tumour protein

WT1aa 3–169UCSCWilm's tumour protein

WT1aa 74–377UCSCWilm's tumour protein

zf-C2H2aa 201–225UCSCZinc finger, C2H2 type

zf-C2H2aa 231–253UCSCZinc finger, C2H2 type

zf-C2H2aa 262–286UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

WT1 transcription factor

HGNC Previous Symbol

GUD

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_024426.6

p.E307_W311delFs

c.920_932del13

Surrounding Variants

1 paper

NM_024426.6

p.W311_N312insFs

c.933_934ins10

1 paper

NM_024426.6

p.N312insFs

c.934_935insG

1 paper

NM_024426.6

p.W311G

c.931T>G

2 papers

NM_024426.6

p.T310delFs

c.930delG

1 paper

NM_024426.6

p.W311fs

c.931_932fs

1 paper

NM_024426.6

p.T310_N312insFs

c.930_934dup5

1 paper

NM_024426.6

p.N312insFs

c.934_935insA

1 paper

NM_024426.6

p.Y300_T310delFs

c.898_929del32

1 paper

NM_024426.6

p.T310I

c.929C>T

1 paper

NM_024426.6

p.Q313insFs

c.937_938insG

1 paper

NM_024426.6

p.T310ins1

c.929_930insGAC

1 paper

NM_024426.6

p.T310A

c.928A>G