Varaico: Literature-Extracted Genetic Variants

WT1

1,404 papers

RefSeq Summary

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the norm...

Pfam Domains

WT1aa 1–321UCSCWilm's tumour protein

WT1aa 3–169UCSCWilm's tumour protein

WT1aa 74–377UCSCWilm's tumour protein

zf-C2H2aa 201–225UCSCZinc finger, C2H2 type

zf-C2H2aa 231–253UCSCZinc finger, C2H2 type

zf-C2H2aa 262–286UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

WT1 transcription factor

HGNC Previous Symbol

GUD

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_024426.6

p.Q305R

c.914A>G

Surrounding Variants

1 paper

NM_024426.6

p.Q305E

c.913C>G

1 paper

NM_024426.6

p.L306insFs

c.917_918insAG

2 papers

NM_024426.6

p.S304F

c.911C>T

1 paper

NM_024426.6

p.S304P

c.910T>C

1 paper

NM_024426.6

p.T303insFs

c.907_908insAT

1 paper

NM_024426.6

p.E307_C308insFs

c.921_922insA

1 paper

NM_024426.6

p.Q301_E307delFs

c.902_920del19

1 paper

NM_024426.6

p.M302_T303insFs

c.906_907insT

1 paper

NM_024426.6

p.M302insFs

c.905_906insTT

1 paper

NM_024426.6

p.M302insFs

c.905_906ins17

1 paper

NM_024426.6

p.C308insFs

c.923_924insCC

1 paper

NM_024426.6

p.C308_M309insFs

c.924_925ins4