Varaico: Literature-Extracted Genetic Variants

WT1

1,404 papers

RefSeq Summary

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the norm...

Pfam Domains

WT1aa 1–321UCSCWilm's tumour protein

WT1aa 3–169UCSCWilm's tumour protein

WT1aa 74–377UCSCWilm's tumour protein

zf-C2H2aa 201–225UCSCZinc finger, C2H2 type

zf-C2H2aa 231–253UCSCZinc finger, C2H2 type

zf-C2H2aa 262–286UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

WT1 transcription factor

HGNC Previous Symbol

GUD

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

7 papers

NM_024426.6

p.R291W

c.871A>T

Surrounding Variants

1 paper

NM_024426.6

p.L289delFs

c.867delC

2 papers

NM_024426.6

p.L289Fs

c.866delinsTAFs

3 papers

NM_024426.6

p.L289Fs

c.865_867delinsAAFs

1 paper

NM_024426.6

p.R291del1

c.871_873delCCT

1 paper

NM_024426.6

p.L288insFs

c.863_864insT

1 paper

NM_024426.6

p.P293_Y294insFs

c.879_880ins8

1 paper

NM_024426.6

p.P293insFs

c.879dupC

1 paper

NM_024426.6

p.L288M

c.862T>A

1 paper

NM_024426.6

p.P293delFs

c.877_878delGG

3 papers

NM_024426.6

p.A287V

c.860C>T

1 paper

NM_024426.6

p.Y294Y

c.882C>T

1 paper

NM_024426.6

p.Q286insFs

c.857_858dupAG