Varaico: Literature-Extracted Genetic Variants

WT1

1,404 papers

RefSeq Summary

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the norm...

Pfam Domains

WT1aa 1–321UCSCWilm's tumour protein

WT1aa 3–169UCSCWilm's tumour protein

WT1aa 74–377UCSCWilm's tumour protein

zf-C2H2aa 201–225UCSCZinc finger, C2H2 type

zf-C2H2aa 231–253UCSCZinc finger, C2H2 type

zf-C2H2aa 262–286UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

WT1 transcription factor

HGNC Previous Symbol

GUD

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_024426.6

p.H276delFs

c.827delT

Surrounding Variants

1 paper

NM_024426.6

p.T277T

c.831C>A

1 paper

NM_024426.6

p.C275F

c.824G>T

1 paper

NM_024426.6

p.C275Y

c.824G>A

4 papers

NM_024426.6

p.P278S

c.832C>T

1 paper

NM_024426.6

p.P278_T279insGAC

c.832_836ins9

1 paper

NM_024426.6

p.G274_C275insFs

c.822_823ins4

1 paper

NM_024426.6

p.C275R

c.823T>C

1 paper

NM_024426.6

p.P278L

c.833C>T

1 paper

NM_024426.6

p.P278P

c.834C>T

2 papers

NM_024426.6

p.G274insFs

c.821_822insG

1 paper

NM_024426.6

p.G274insFs

c.821_822insA

1 paper

NM_024426.6

p.G274A

c.821G>C