Varaico: Literature-Extracted Genetic Variants

WT1

1,404 papers

RefSeq Summary

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the norm...

Pfam Domains

WT1aa 1–321UCSCWilm's tumour protein

WT1aa 3–169UCSCWilm's tumour protein

WT1aa 74–377UCSCWilm's tumour protein

zf-C2H2aa 201–225UCSCZinc finger, C2H2 type

zf-C2H2aa 231–253UCSCZinc finger, C2H2 type

zf-C2H2aa 262–286UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

WT1 transcription factor

HGNC Previous Symbol

GUD

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_024426.6

p.P269insFs

c.805_806ins5

Surrounding Variants

1 paper

NM_024426.6

p.P270L

c.809C>T

1 paper

NM_024426.6

p.V268L

c.802G>T

1 paper

NM_024426.6

p.P271fs

c.811_812fs

1 paper

NM_024426.6

p.P271S

c.811C>T

1 paper

NM_024426.6

p.P271T

c.811C>A

1 paper

NM_024426.6

p.P271L

c.812C>T

1 paper

NM_001198551.2

p.S50*

c.149C>A

2 papers

NM_024426.6

p.P271insFs

c.812dupC

1 paper

NM_024426.6

p.P271delFs

c.812delG

1 paper

NM_024426.6

p.V272F

c.814G>T

1 paper

NM_024426.6

p.V272L

c.814G>C

1 paper

NM_024426.6

p.Y266*

c.798C>G