Varaico: Literature-Extracted Genetic Variants

WT1

1,404 papers

RefSeq Summary

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the norm...

Pfam Domains

WT1aa 1–321UCSCWilm's tumour protein

WT1aa 3–169UCSCWilm's tumour protein

WT1aa 74–377UCSCWilm's tumour protein

zf-C2H2aa 201–225UCSCZinc finger, C2H2 type

zf-C2H2aa 231–253UCSCZinc finger, C2H2 type

zf-C2H2aa 262–286UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

WT1 transcription factor

HGNC Previous Symbol

GUD

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

9 papers

NM_024426.6

p.Q220*

c.658C>T

Surrounding Variants

1 paper

NM_024426.6

p.G221Splc

c.661+1G>A

1 paper

NM_024426.6

p.R218H

c.653G>A

1 paper

NM_024426.6

p.R218C

c.652C>T

1 paper

NM_024426.6

p.I217insFs

c.649_650insG

1 paper

NM_024426.6

p.P215S

c.643C>T

1 paper

NM_024426.6

p.G221Splc

c.661+13G>C

1 paper

NM_024426.6

p.Q214delFs

c.641delT

9 papers

NM_024426.6

p.Q214*

c.640C>T

1 paper

NM_024426.6

p.Q214insFs

c.640_641insT

1 paper

NM_024426.6

p.S213delFs

c.638delC

1 paper

NM_024426.6

p.L207_S213delFs

c.620_638del19

1 paper

NM_024426.6

p.S213I

c.638G>T