Varaico: Literature-Extracted Genetic Variants

WT1

1,404 papers

RefSeq Summary

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the norm...

Pfam Domains

WT1aa 1–321UCSCWilm's tumour protein

WT1aa 3–169UCSCWilm's tumour protein

WT1aa 74–377UCSCWilm's tumour protein

zf-C2H2aa 201–225UCSCZinc finger, C2H2 type

zf-C2H2aa 231–253UCSCZinc finger, C2H2 type

zf-C2H2aa 262–286UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

WT1 transcription factor

HGNC Previous Symbol

GUD

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_024426.6

p.L207insFs

c.619_620insGG

Surrounding Variants

2 papers

NM_024426.6

p.L207insFs

c.619_620insG

1 paper

NM_024426.6

p.L207R

c.620T>G

1 paper

NM_024426.6

p.Y206*

c.618C>G

1 paper

NM_024426.6

p.Y206*

c.618C>A

1 paper

NM_024426.6

p.P205_L207delins

c.614_621delinsTT

1 paper

NM_024426.6

p.P208S

c.622C>T

1 paper

NM_024426.6

p.Y206fs

c.616_617fs

1 paper

NM_024426.6

p.P208L

c.623C>T

1 paper

NM_024426.6

p.P205L

c.614C>T

1 paper

NM_024426.6

p.P205insFs

c.614_615ins5

1 paper

NM_024426.6

p.P205S

c.613C>T

1 paper

NM_024426.6

p.S209fs

c.625_626fs