Varaico: Literature-Extracted Genetic Variants

WT1

1,404 papers

RefSeq Summary

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the norm...

Pfam Domains

WT1aa 1–321UCSCWilm's tumour protein

WT1aa 3–169UCSCWilm's tumour protein

WT1aa 74–377UCSCWilm's tumour protein

zf-C2H2aa 201–225UCSCZinc finger, C2H2 type

zf-C2H2aa 231–253UCSCZinc finger, C2H2 type

zf-C2H2aa 262–286UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

WT1 transcription factor

HGNC Previous Symbol

GUD

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_024426.6

p.S194*

c.581C>G

Surrounding Variants

1 paper

NM_024426.6

p.S194*

c.581C>A

1 paper

NM_024426.6

p.S194delFs

c.580_581delGA

1 paper

NM_024426.6

p.Q192_A193insFs

c.574_578dup5

1 paper

NM_024426.6

p.A193T

c.577G>A

1 paper

NM_024426.6

p.Q192delFs

c.575_576delCT

1 paper

NM_024426.6

p.S195fs

c.583_584fs

1 paper

NM_024426.6

p.Q192H

c.576G>T

1 paper

NM_024426.6

p.Q192H

c.576G>C

2 papers

NM_024426.6

p.G196S

c.586G>A

1 paper

NM_024426.6

p.S195delFs

c.584_585delGG

1 paper

NM_024426.6

p.G196A

c.587G>C

1 paper

NM_024426.6

p.Q192insFs

c.575_576insT