Varaico: Literature-Extracted Genetic Variants

WT1

1,404 papers

RefSeq Summary

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the norm...

Pfam Domains

WT1aa 1–321UCSCWilm's tumour protein

WT1aa 3–169UCSCWilm's tumour protein

WT1aa 74–377UCSCWilm's tumour protein

zf-C2H2aa 201–225UCSCZinc finger, C2H2 type

zf-C2H2aa 231–253UCSCZinc finger, C2H2 type

zf-C2H2aa 262–286UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

WT1 transcription factor

HGNC Previous Symbol

GUD

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_024426.6

p.P188L

c.563C>T

Surrounding Variants

1 paper

NM_024426.6

p.P188S

c.562C>T

1 paper

NM_024426.6

p.P187delFs

c.559delG

1 paper

NM_024426.6

p.P189Q

c.566C>A

2 papers

NM_024426.6

p.P187S

c.559C>T

1 paper

NM_024426.6

p.F185_P187Fs

c.554_559delinsTGTGFs

1 paper

NM_024426.6

p.G186fs

c.556_557fs

1 paper

NM_024426.6

p.P190A

c.568C>G

1 paper

NM_024426.6

p.G186D

c.557G>A

1 paper

NM_024426.6

p.P190L

c.569C>T

1 paper

NM_024426.6

p.P189_P190delFs

c.567_568delGC

1 paper

NM_024426.6

p.F185delFs

c.555delG

1 paper

NM_024426.6

p.P190P

c.570C>T