Varaico: Literature-Extracted Genetic Variants

WT1

1,404 papers

RefSeq Summary

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the norm...

Pfam Domains

WT1aa 1–321UCSCWilm's tumour protein

WT1aa 3–169UCSCWilm's tumour protein

WT1aa 74–377UCSCWilm's tumour protein

zf-C2H2aa 201–225UCSCZinc finger, C2H2 type

zf-C2H2aa 231–253UCSCZinc finger, C2H2 type

zf-C2H2aa 262–286UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

WT1 transcription factor

HGNC Previous Symbol

GUD

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_024426.6

p.G183R

c.547G>C

Surrounding Variants

1 paper

NM_024426.6

p.G183R

c.547G>A

1 paper

NM_024426.6

p.Q172_Y182del11

c.514_545del33

1 paper

NM_024426.6

p.G183V

c.548G>T

1 paper

NM_024426.6

p.G183insFs

c.548_549ins35

2 papers

NM_024426.6

p.Y182*

c.546C>G

2 papers

NM_024426.6

p.Y182*

c.546C>A

1 paper

NM_024426.6

p.G183_P184ins11

c.549_550ins33

1 paper

NM_024426.6

p.G183_P184insFs

c.549_550ins35

1 paper

NM_024426.6

p.R181del1

c.541_543delGCG

2 papers

NM_024426.6

p.P184S

c.550C>T

1 paper

NM_024426.6

p.P184L

c.551C>T

1 paper

NM_024426.6

p.P184insFs

c.551_552insG