Varaico: Literature-Extracted Genetic Variants

WT1

1,404 papers

RefSeq Summary

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the norm...

Pfam Domains

WT1aa 1–321UCSCWilm's tumour protein

WT1aa 3–169UCSCWilm's tumour protein

WT1aa 74–377UCSCWilm's tumour protein

zf-C2H2aa 201–225UCSCZinc finger, C2H2 type

zf-C2H2aa 231–253UCSCZinc finger, C2H2 type

zf-C2H2aa 262–286UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

WT1 transcription factor

HGNC Previous Symbol

GUD

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_024426.6

p.C180insFs

c.538_539insTC

Surrounding Variants

1 paper

NM_024426.6

p.A179delFs

c.536delG

3 papers

NM_024426.6

p.R181C

c.541C>T

1 paper

NM_024426.6

p.C180_R181insFs

c.540_541insT

2 papers

NM_024426.6

p.A179D

c.536C>A

1 paper

NM_024426.6

p.R181del1

c.541_543delGCG

1 paper

NM_024426.6

p.G178V

c.533G>T

2 papers

NM_024426.6

p.Y182*

c.546C>G

2 papers

NM_024426.6

p.Y182*

c.546C>A

1 paper

NM_024426.6

p.G183R

c.547G>C

1 paper

NM_024426.6

p.G183R

c.547G>A

1 paper

NM_024426.6

p.Q172_Y182del11

c.514_545del33

2 papers

NM_024426.6

p.A177A

c.531C>A