Varaico: Literature-Extracted Genetic Variants

WT1

1,404 papers

RefSeq Summary

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the norm...

Pfam Domains

WT1aa 1–321UCSCWilm's tumour protein

WT1aa 3–169UCSCWilm's tumour protein

WT1aa 74–377UCSCWilm's tumour protein

zf-C2H2aa 201–225UCSCZinc finger, C2H2 type

zf-C2H2aa 231–253UCSCZinc finger, C2H2 type

zf-C2H2aa 262–286UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

WT1 transcription factor

HGNC Previous Symbol

GUD

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_024426.6

p.S170T

c.508T>A

Surrounding Variants

1 paper

NM_024426.6

p.F169_S170insFs

c.505_508dup4

1 paper

NM_024426.6

p.S170fs

c.508_509fs

1 paper

NM_024426.6

p.S170delins

c.509_510delinsAA

1 paper

NM_024426.6

p.H168del1

c.502_504delGTG

1 paper

NM_024426.6

p.S170insFs

c.509dupC

1 paper

NM_024426.6

p.G171_Q172insCTG

c.511_515ins9

1 paper

NM_024426.6

p.G171R

c.511G>C

1 paper

NM_024426.6

p.G171V

c.512G>T

1 paper

NM_024426.6

p.H168Q

c.504C>A

1 paper

NM_024426.6

p.H168P

c.503A>C

1 paper

NM_024426.6

p.Q172fs

c.514_515fs

2 papers

NM_024426.6

p.Q172*

c.514C>T