Varaico: Literature-Extracted Genetic Variants

WT1

1,404 papers

RefSeq Summary

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the norm...

Pfam Domains

WT1aa 1–321UCSCWilm's tumour protein

WT1aa 3–169UCSCWilm's tumour protein

WT1aa 74–377UCSCWilm's tumour protein

zf-C2H2aa 201–225UCSCZinc finger, C2H2 type

zf-C2H2aa 231–253UCSCZinc finger, C2H2 type

zf-C2H2aa 262–286UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

WT1 transcription factor

HGNC Previous Symbol

GUD

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_024426.6

p.L162P

c.485T>C

Surrounding Variants

2 papers

NM_024426.6

p.L162R

c.485T>G

1 paper

NM_024426.6

p.L162Q

c.485T>A

1 paper

NM_024426.6

p.C161_L162insFs

c.483_484insCA

2 papers

NM_024426.6

p.S163fs

c.487_488fs

1 paper

NM_024426.6

p.S163insFs

c.487_488ins13

1 paper

NM_024426.6

p.Q160Fs

c.480delinsGGCFs

1 paper

NM_024426.6

p.Q160*

c.478C>T

1 paper

NM_024426.6

p.E159fs

c.475_476fs

1 paper

NM_024426.6

p.L162_F165delFs

c.486_493del8

1 paper

NM_024426.6

p.E159G

c.476A>G

1 paper

NM_024426.6

p.E159delFs

c.475delC

1 paper

NM_024426.6

p.E159Q

c.475G>C