Varaico: Literature-Extracted Genetic Variants

WT1

1,404 papers

RefSeq Summary

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the norm...

Pfam Domains

WT1aa 1–321UCSCWilm's tumour protein

WT1aa 3–169UCSCWilm's tumour protein

WT1aa 74–377UCSCWilm's tumour protein

zf-C2H2aa 201–225UCSCZinc finger, C2H2 type

zf-C2H2aa 231–253UCSCZinc finger, C2H2 type

zf-C2H2aa 262–286UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

WT1 transcription factor

HGNC Previous Symbol

GUD

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_024426.6

p.H157delFs

c.469delG

Surrounding Variants

1 paper

NM_024426.6

p.H157R

c.470A>G

1 paper

NM_024426.6

p.P156_H157delFs

c.466_469del4

1 paper

NM_024426.6

p.H157Y

c.469C>T

1 paper

NM_024426.6

p.P156delFs

c.468delC

2 papers

NM_024426.6

p.E158*

c.472G>T

1 paper

NM_024426.6

p.P156insFs

c.467dupC

1 paper

NM_024426.6

p.P156Fs

c.468delinsTGAGACFs

1 paper

NM_024426.6

p.P156insFs

c.467_468insT

1 paper

NM_024426.6

p.P156insFs

c.467_468ins8

1 paper

NM_024426.6

p.E158insFs

c.472_473insG

1 paper

NM_024426.6

p.H157_E158insFs

c.469_473dup5

1 paper

NM_024426.6

p.E159Q

c.475G>C