Varaico: Literature-Extracted Genetic Variants

WT1

1,404 papers

RefSeq Summary

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the norm...

Pfam Domains

WT1aa 1–321UCSCWilm's tumour protein

WT1aa 3–169UCSCWilm's tumour protein

WT1aa 74–377UCSCWilm's tumour protein

zf-C2H2aa 201–225UCSCZinc finger, C2H2 type

zf-C2H2aa 231–253UCSCZinc finger, C2H2 type

zf-C2H2aa 262–286UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

WT1 transcription factor

HGNC Previous Symbol

GUD

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_024426.6

p.Q147insFs

c.440_441insT

Surrounding Variants

2 papers

NM_024426.6

p.Q147insFs

c.440_441insCC

1 paper

NM_024426.6

p.Q147_E148insFs

c.441_442ins7

2 papers

NM_024426.6

p.Q147delFs

c.440delT

2 papers

NM_024426.6

p.E148*

c.442G>T

1 paper

NM_024426.6

p.S143_K146delFs

c.428_437del10

1 paper

NM_024426.6

p.E148Fs

c.444delinsAGACTFs

1 paper

NM_024426.6

p.K146*

c.436A>T

1 paper

NM_024426.6

p.K146E

c.436A>G

1 paper

NM_024426.6

p.P149insFs

c.445_446ins5

1 paper

NM_024426.6

p.E148delFs

c.443_444delCT

1 paper

NM_024426.6

p.I145delFs

c.433delT

2 papers

NM_024426.6

p.P149L

c.446C>T