Varaico: Literature-Extracted Genetic Variants

WT1

1,404 papers

RefSeq Summary

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the norm...

Pfam Domains

WT1aa 1–321UCSCWilm's tumour protein

WT1aa 3–169UCSCWilm's tumour protein

WT1aa 74–377UCSCWilm's tumour protein

zf-C2H2aa 201–225UCSCZinc finger, C2H2 type

zf-C2H2aa 231–253UCSCZinc finger, C2H2 type

zf-C2H2aa 262–286UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

WT1 transcription factor

HGNC Previous Symbol

GUD

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_024426.6

p.F144fs

c.430_431fs

Surrounding Variants

1 paper

NM_024426.6

p.F144L

c.432C>A

1 paper

NM_024426.6

p.I145fs

c.433_434fs

1 paper

NM_024426.6

p.S143insFs

c.429dupC

1 paper

NM_024426.6

p.I145delFs

c.433delT

1 paper

NM_024426.6

p.S143_F144insFs

c.429_430ins7

1 paper

NM_024426.6

p.P141_H142delFs

c.423_426del4

1 paper

NM_024426.6

p.S143F

c.428C>T

2 papers

NM_024426.6

p.S143C

c.428C>G

1 paper

NM_024426.6

p.K146*

c.436A>T

1 paper

NM_024426.6

p.K146E

c.436A>G

1 paper

NM_024426.6

p.S143_K146delFs

c.428_437del10

1 paper

NM_024426.6

p.H142L

c.425A>T