Varaico: Literature-Extracted Genetic Variants

WT1

1,404 papers

RefSeq Summary

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the norm...

Pfam Domains

WT1aa 1–321UCSCWilm's tumour protein

WT1aa 3–169UCSCWilm's tumour protein

WT1aa 74–377UCSCWilm's tumour protein

zf-C2H2aa 201–225UCSCZinc finger, C2H2 type

zf-C2H2aa 231–253UCSCZinc finger, C2H2 type

zf-C2H2aa 262–286UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

WT1 transcription factor

HGNC Previous Symbol

GUD

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_024426.6

p.P141L

c.422C>T

Surrounding Variants

1 paper

NM_024426.6

p.P141R

c.422C>G

1 paper

NM_024426.6

p.P141insFs

c.422_423ins7

1 paper

NM_024426.6

p.P141insFs

c.422_423insGG

1 paper

NM_024426.6

p.P141insFs

c.422_423ins4

3 papers

NM_024426.6

p.P141insFs

c.422_423insC

1 paper

NM_024426.6

p.P140_P141del1

c.420_422delGGC

1 paper

NM_024426.6

p.P141insFs

c.421_422insT

1 paper

NM_024426.6

p.P141T

c.421C>A

1 paper

NM_024426.6

p.P140insFs

c.418dupC

2 papers

NM_024426.6

p.H142Y

c.424C>T

2 papers

NM_024426.6

p.P141insFs

c.423dupT

1 paper

NM_024426.6

p.P141_H142insFs

c.423_424insTT