Varaico: Literature-Extracted Genetic Variants

WT1

1,404 papers

RefSeq Summary

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the norm...

Pfam Domains

WT1aa 1–321UCSCWilm's tumour protein

WT1aa 3–169UCSCWilm's tumour protein

WT1aa 74–377UCSCWilm's tumour protein

zf-C2H2aa 201–225UCSCZinc finger, C2H2 type

zf-C2H2aa 231–253UCSCZinc finger, C2H2 type

zf-C2H2aa 262–286UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

WT1 transcription factor

HGNC Previous Symbol

GUD

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_024426.6

p.P131_A132ins0

c.393_395dupGGC

Surrounding Variants

1 paper

NM_024426.6

p.A132insFs

c.395dupC

1 paper

NM_024426.6

p.A132A

c.396T>A

2 papers

NM_024426.6

p.A132delFs

c.395delG

2 papers

NM_024426.6

p.S123_A132delFs

c.367_394del28

2 papers

NM_024426.6

p.P133L

c.398C>T

1 paper

NM_024426.6

p.P133insFs

c.398_399insT

1 paper

NM_024426.6

p.G126_P131ins2

c.378_392dup15

2 papers

NM_024426.6

p.P131S

c.391C>T

1 paper

NM_024426.6

p.P134L

c.401C>T

1 paper

NM_024426.6

p.P131T

c.391C>A

1 paper

NM_024426.6

p.P130P

c.390A>C

4 papers

NM_024426.6

p.P130L

c.389C>T