Varaico: Literature-Extracted Genetic Variants

WT1

1,404 papers

RefSeq Summary

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the norm...

Pfam Domains

WT1aa 1–321UCSCWilm's tumour protein

WT1aa 3–169UCSCWilm's tumour protein

WT1aa 74–377UCSCWilm's tumour protein

zf-C2H2aa 201–225UCSCZinc finger, C2H2 type

zf-C2H2aa 231–253UCSCZinc finger, C2H2 type

zf-C2H2aa 262–286UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

WT1 transcription factor

HGNC Previous Symbol

GUD

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_024426.6

p.P130P

c.390A>C

Surrounding Variants

4 papers

NM_024426.6

p.P130L

c.389C>T

2 papers

NM_024426.6

p.P131S

c.391C>T

1 paper

NM_024426.6

p.P131T

c.391C>A

1 paper

NM_024426.6

p.P130insFs

c.388_389insAC

1 paper

NM_024426.6

p.P130fs

c.388_389fs

1 paper

NM_024426.6

p.G126_P131ins2

c.378_392dup15

1 paper

NM_024426.6

p.P129fs

c.385_386fs

1 paper

NM_024426.6

p.P127_P129delFs

c.379_385del7

6 papers

NM_024426.6

p.P129L

c.386C>T

1 paper

NM_024426.6

p.G126_P129delFs

c.376_385del10

1 paper

NM_024426.6

p.S123_P129delFs

c.369_385del17

2 papers

NM_024426.6

p.P129S

c.385C>T