Varaico: Literature-Extracted Genetic Variants

WT1

1,404 papers

RefSeq Summary

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the norm...

Pfam Domains

WT1aa 1–321UCSCWilm's tumour protein

WT1aa 3–169UCSCWilm's tumour protein

WT1aa 74–377UCSCWilm's tumour protein

zf-C2H2aa 201–225UCSCZinc finger, C2H2 type

zf-C2H2aa 231–253UCSCZinc finger, C2H2 type

zf-C2H2aa 262–286UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

WT1 transcription factor

HGNC Previous Symbol

GUD

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_024426.6

p.G126D

c.377G>A

Surrounding Variants

1 paper

NM_024426.6

p.G126G

c.378C>G

1 paper

NM_024426.6

p.G126fs

c.376_377fs

1 paper

NM_024426.6

p.G126fs

c.376_377fs

1 paper

NM_024426.6

p.P127S

c.379C>T

1 paper

NM_024426.6

p.G125G

c.375C>G

1 paper

NM_024426.6

p.G125G

c.375C>A

1 paper

NM_024426.6

p.S123_G125delFs

c.367_374del8

1 paper

NM_024426.6

p.G122_L124del3

c.364_371del9

1 paper

NM_024426.6

p.G125V

c.374G>T

1 paper

NM_024426.6

p.G125insFs

c.374_375ins4

1 paper

NM_024426.6

p.P127fs

c.379_380fs

1 paper

NM_024426.6

p.A128T

c.382G>A