Varaico: Literature-Extracted Genetic Variants

WT1

1,404 papers

RefSeq Summary

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the norm...

Pfam Domains

WT1aa 1–321UCSCWilm's tumour protein

WT1aa 3–169UCSCWilm's tumour protein

WT1aa 74–377UCSCWilm's tumour protein

zf-C2H2aa 201–225UCSCZinc finger, C2H2 type

zf-C2H2aa 231–253UCSCZinc finger, C2H2 type

zf-C2H2aa 262–286UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

WT1 transcription factor

HGNC Previous Symbol

GUD

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_024426.6

p.Y121H

c.361T>C

Surrounding Variants

1 paper

NM_024426.6

p.Y121_G122insFs

c.363_364insA

1 paper

NM_024426.6

p.S119insFs

c.356_357insCG

1 paper

NM_024426.6

p.A120P

c.358G>C

1 paper

NM_024426.6

p.A120T

c.358G>A

1 paper

NM_024426.6

p.S119*

c.356C>A

1 paper

NM_024426.6

p.G122insFs

c.366dupG

1 paper

NM_024426.6

p.S119A

c.355T>G

1 paper

NM_024426.6

p.G122del1

c.364_366delCCC

1 paper

NM_024426.6

p.S119fs

c.355_356fs

2 papers

NM_024426.6

p.S123L

c.368C>T

2 papers

NM_024426.6

p.A118V

c.353C>T

1 paper

NM_024426.6

p.A118D

c.353C>A