Varaico: Literature-Extracted Genetic Variants

WT1

1,404 papers

RefSeq Summary

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the norm...

Pfam Domains

WT1aa 1–321UCSCWilm's tumour protein

WT1aa 3–169UCSCWilm's tumour protein

WT1aa 74–377UCSCWilm's tumour protein

zf-C2H2aa 201–225UCSCZinc finger, C2H2 type

zf-C2H2aa 231–253UCSCZinc finger, C2H2 type

zf-C2H2aa 262–286UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

WT1 transcription factor

HGNC Previous Symbol

GUD

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_024426.6

p.P116L

c.347C>T

Surrounding Variants

1 paper

NM_024426.6

p.P116fs

c.346_347fs

2 papers

NM_024426.6

p.P116delFs

c.347delG

1 paper

NM_024426.6

p.P115del1

c.343_345delGGG

1 paper

NM_024426.6

p.P116T

c.346C>A

2 papers

NM_024426.6

p.G117R

c.349G>C

2 papers

NM_024426.6

p.G117S

c.349G>A

1 paper

NM_024426.6

p.P115L

c.344C>T

1 paper

NM_024426.6

p.P115H

c.344C>A

1 paper

NM_024426.6

p.A118P

c.352G>C

1 paper

NM_024426.6

p.V110_F113delFs

c.329_338del10

1 paper

NM_024426.6

p.V110_P115delins

c.328_343delinsTAAC

2 papers

NM_024426.6

p.A118V

c.353C>T