Varaico: Literature-Extracted Genetic Variants

WT1

1,404 papers

RefSeq Summary

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the norm...

Pfam Domains

WT1aa 1–321UCSCWilm's tumour protein

WT1aa 3–169UCSCWilm's tumour protein

WT1aa 74–377UCSCWilm's tumour protein

zf-C2H2aa 201–225UCSCZinc finger, C2H2 type

zf-C2H2aa 231–253UCSCZinc finger, C2H2 type

zf-C2H2aa 262–286UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

WT1 transcription factor

HGNC Previous Symbol

GUD

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_024426.6

p.D112E

c.336C>G

Surrounding Variants

1 paper

NM_024426.6

p.D112D

c.336C>T

1 paper

NM_024426.6

p.D112E

c.336C>A

1 paper

NM_024426.6

p.F113I

c.337T>A

1 paper

NM_024426.6

p.F113fs

c.337_338fs

1 paper

NM_024426.6

p.D112delFs

c.334delC

1 paper

NM_024426.6

p.D112N

c.334G>A

1 paper

NM_024426.6

p.Q106_L111del6

c.316_332del18

1 paper

NM_024426.6

p.F113Fs

c.339delinsAATFs

1 paper

NM_024426.6

p.P109_F113delFs

c.326_338del13

1 paper

NM_024426.6

p.L111delFs

c.332delA

1 paper

NM_024426.6

p.L111R

c.332T>G

1 paper

NM_024426.6

p.L111Q

c.332T>A