Varaico: Literature-Extracted Genetic Variants

WT1

1,404 papers

RefSeq Summary

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the norm...

Pfam Domains

WT1aa 1–321UCSCWilm's tumour protein

WT1aa 3–169UCSCWilm's tumour protein

WT1aa 74–377UCSCWilm's tumour protein

zf-C2H2aa 201–225UCSCZinc finger, C2H2 type

zf-C2H2aa 231–253UCSCZinc finger, C2H2 type

zf-C2H2aa 262–286UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

WT1 transcription factor

HGNC Previous Symbol

GUD

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_024426.6

p.Q106K

c.316C>A

Surrounding Variants

1 paper

NM_024426.6

p.Q106L

c.317A>T

1 paper

NM_024426.6

p.Q106P

c.317A>C

1 paper

NM_024426.6

p.W107R

c.319T>A

1 paper

NM_024426.6

p.A105_Q106delFs

c.313_317del5

1 paper

NM_024426.6

p.A105T

c.313G>A

1 paper

NM_024426.6

p.W107*

c.320G>A

2 papers

NM_024426.6

p.W107*

c.321G>A

1 paper

NM_024426.6

p.A104V

c.311C>T

1 paper

NM_024426.6

p.A108V

c.323C>T

1 paper

NM_024426.6

p.G103delFs

c.307delC

1 paper

NM_024426.6

p.A108A

c.324G>C

1 paper

NM_024426.6

p.G103D

c.308G>A