Varaico: Literature-Extracted Genetic Variants

WT1

1,404 papers

RefSeq Summary

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the norm...

Pfam Domains

WT1aa 1–321UCSCWilm's tumour protein

WT1aa 3–169UCSCWilm's tumour protein

WT1aa 74–377UCSCWilm's tumour protein

zf-C2H2aa 201–225UCSCZinc finger, C2H2 type

zf-C2H2aa 231–253UCSCZinc finger, C2H2 type

zf-C2H2aa 262–286UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

WT1 transcription factor

HGNC Previous Symbol

GUD

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_024426.6

p.A98A

c.294C>A

Surrounding Variants

2 papers

NM_024426.6

p.A98A

c.294C>T

1 paper

NM_024426.6

p.A98V

c.293C>T

1 paper

NM_024426.6

p.L99Q

c.296T>A

1 paper

NM_024426.6

p.L99delFs

c.295delG

1 paper

NM_024426.6

p.A98_L99del1

c.293_295delGGG

1 paper

NM_024426.6

p.A98T

c.292G>A

1 paper

NM_024426.6

p.C97_A98insFs

c.291_292insG

1 paper

NM_024426.6

p.L99delFs

c.296delA

1 paper

NM_024426.6

p.C97delFs

c.289delA

2 papers

NM_024426.6

p.P100R

c.299C>G

1 paper

NM_024426.6

p.G96G

c.288C>T

1 paper

NM_024426.6

p.G96D

c.287G>A