Varaico: Literature-Extracted Genetic Variants

WT1

1,404 papers

RefSeq Summary

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the norm...

Pfam Domains

WT1aa 1–321UCSCWilm's tumour protein

WT1aa 3–169UCSCWilm's tumour protein

WT1aa 74–377UCSCWilm's tumour protein

zf-C2H2aa 201–225UCSCZinc finger, C2H2 type

zf-C2H2aa 231–253UCSCZinc finger, C2H2 type

zf-C2H2aa 262–286UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

WT1 transcription factor

HGNC Previous Symbol

GUD

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_024426.6

p.V88I

c.262G>A

Surrounding Variants

1 paper

NM_024426.6

p.A87A

c.261C>A

2 papers

NM_024426.6

p.L84_P86del3

c.250_257del9

1 paper

NM_024426.6

p.P89S

c.265C>T

1 paper

NM_024426.6

p.P89T

c.265C>A

1 paper

NM_024426.6

p.P86P

c.258C>A

1 paper

NM_024426.6

p.P86L

c.257C>T

2 papers

NM_024426.6

p.L84_P86delFs

c.252_256del5

1 paper

NM_024426.6

p.L81_L85del0

c.241_255del15

1 paper

NM_024426.6

p.L85L

c.255G>T

1 paper

NM_024426.6

p.L85delFs

c.253_254delAG

1 paper

NM_024426.6

p.L84Q

c.251T>A

1 paper

NM_024426.6

p.L91L

c.273G>A