Varaico: Literature-Extracted Genetic Variants

WT1

1,404 papers

RefSeq Summary

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the norm...

Pfam Domains

WT1aa 1–321UCSCWilm's tumour protein

WT1aa 3–169UCSCWilm's tumour protein

WT1aa 74–377UCSCWilm's tumour protein

zf-C2H2aa 201–225UCSCZinc finger, C2H2 type

zf-C2H2aa 231–253UCSCZinc finger, C2H2 type

zf-C2H2aa 262–286UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

WT1 transcription factor

HGNC Previous Symbol

GUD

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_024426.6

p.D77_V78insFs

c.231_232dupCG

Surrounding Variants

1 paper

NM_024426.6

p.D77_V78insFs

c.231_232insC

1 paper

NM_024426.6

p.V78fs

c.232_233fs

1 paper

NM_024426.6

p.M74_D77delFs

c.221_231del11

1 paper

NM_024426.6

p.R79W

c.235C>T

1 paper

NM_024426.6

p.R79Q

c.236G>A

1 paper

NM_024426.6

p.D80N

c.238G>A

1 paper

NM_024426.6

p.S76S

c.228C>T

1 paper

NM_024426.6

p.S76S

c.228C>A

1 paper

NM_024426.6

p.S76F

c.227C>T

2 papers

NM_024426.6

p.L81L

c.241C>T

1 paper

NM_024426.6

p.L81V

c.241C>G

1 paper

NM_024426.6

p.G75_S76insFs

c.225_226insAC