Varaico: Literature-Extracted Genetic Variants

WT1

1,404 papers

RefSeq Summary

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the norm...

Pfam Domains

WT1aa 1–321UCSCWilm's tumour protein

WT1aa 3–169UCSCWilm's tumour protein

WT1aa 74–377UCSCWilm's tumour protein

zf-C2H2aa 201–225UCSCZinc finger, C2H2 type

zf-C2H2aa 231–253UCSCZinc finger, C2H2 type

zf-C2H2aa 262–286UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

WT1 transcription factor

HGNC Previous Symbol

GUD

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_024426.6

p.Q72*

c.214C>T

Surrounding Variants

1 paper

NM_024426.6

p.E70_P71del2

c.208_212del6

1 paper

NM_024426.6

p.G68_P71del4

c.202_212del12

2 papers

NM_024426.6

p.P71P

c.213G>T

1 paper

NM_024426.6

p.Q72Q

c.216G>A

1 paper

NM_024426.6

p.P71L

c.212C>T

3 papers

NM_024426.6

p.P71S

c.211C>T

1 paper

NM_024426.6

p.E70delFs

c.209_210delCT

1 paper

NM_024426.6

p.Q73L

c.218A>T

1 paper

NM_024426.6

p.Q73P

c.218A>C

9 papers

NM_024426.6

p.E70*

c.208G>T

2 papers

NM_024426.6

p.E70K

c.208G>A

1 paper

NM_024426.6

p.S69Fs

c.206delinsCCFs