Varaico: Literature-Extracted Genetic Variants

WT1

1,404 papers

RefSeq Summary

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the norm...

Pfam Domains

WT1aa 1–321UCSCWilm's tumour protein

WT1aa 3–169UCSCWilm's tumour protein

WT1aa 74–377UCSCWilm's tumour protein

zf-C2H2aa 201–225UCSCZinc finger, C2H2 type

zf-C2H2aa 231–253UCSCZinc finger, C2H2 type

zf-C2H2aa 262–286UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

WT1 transcription factor

HGNC Previous Symbol

GUD

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_024426.6

p.S63C

c.187A>T

Surrounding Variants

1 paper

NM_024426.6

p.E56_R62del0

c.168_185del18

1 paper

NM_024426.6

p.R62K

c.185G>A

1 paper

NM_024426.6

p.R64C

c.190C>T

1 paper

NM_024426.6

p.R62G

c.184A>G

1 paper

NM_024426.6

p.R64H

c.191G>A

1 paper

NM_024426.6

p.L58_R61delFs

c.172_182del11

1 paper

NM_024426.6

p.G65V

c.194G>T

1 paper

NM_024426.6

p.G60G

c.180C>T

1 paper

NM_024426.6

p.G60A

c.179G>C

1 paper

NM_024426.6

p.G60C

c.178G>T

6 papers

NM_024426.6

p.G60R

c.178G>C

3 papers

NM_024426.6

p.G60S

c.178G>A