Varaico: Literature-Extracted Genetic Variants

WT1

1,404 papers

RefSeq Summary

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the norm...

Pfam Domains

WT1aa 1–321UCSCWilm's tumour protein

WT1aa 3–169UCSCWilm's tumour protein

WT1aa 74–377UCSCWilm's tumour protein

zf-C2H2aa 201–225UCSCZinc finger, C2H2 type

zf-C2H2aa 231–253UCSCZinc finger, C2H2 type

zf-C2H2aa 262–286UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

WT1 transcription factor

HGNC Previous Symbol

GUD

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_024426.6

p.R57P

c.170G>C

Surrounding Variants

1 paper

NM_024426.6

p.R57_L58ins1

c.171_172insCTG

1 paper

NM_024426.6

p.R57_L58insL

c.169_173ins3

1 paper

NM_024426.6

p.E56delFs

c.167delT

1 paper

NM_024426.6

p.L58delFs

c.172delG

1 paper

NM_024426.6

p.L58_Q59delins

c.174_175delinsAA

1 paper

NM_024426.6

p.A55_L58delFs

c.164_173del10

1 paper

NM_024426.6

p.A55V

c.164C>T

1 paper

NM_024426.6

p.R57_L58del2

c.169_173del6

1 paper

NM_024426.6

p.A55T

c.163G>A

1 paper

NM_024426.6

p.G60C

c.178G>T

6 papers

NM_024426.6

p.G60R

c.178G>C

3 papers

NM_024426.6

p.G60S

c.178G>A