Varaico: Literature-Extracted Genetic Variants

WT1

1,404 papers

RefSeq Summary

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the norm...

Pfam Domains

WT1aa 1–321UCSCWilm's tumour protein

WT1aa 3–169UCSCWilm's tumour protein

WT1aa 74–377UCSCWilm's tumour protein

zf-C2H2aa 201–225UCSCZinc finger, C2H2 type

zf-C2H2aa 231–253UCSCZinc finger, C2H2 type

zf-C2H2aa 262–286UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

WT1 transcription factor

HGNC Previous Symbol

GUD

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_024426.6

p.A46delFs

c.136delC

Surrounding Variants

1 paper

NM_024426.6

p.A46V

c.137C>T

1 paper

NM_024426.6

p.W45_A46delFs

c.135_136delCC

2 papers

NM_024426.6

p.A46T

c.136G>A

3 papers

NM_024426.6

p.A46fs

c.136_137fs

1 paper

NM_024426.6

p.W45_A46insFs

c.135_136insC

2 papers

NM_024426.6

p.W45*

c.135G>A

1 paper

NM_024426.6

p.K47R

c.140A>G

1 paper

NM_024426.6

p.K47K

c.141G>A

1 paper

NM_024426.6

p.K47delFs

c.140_141delCT

2 papers

NM_024426.6

p.I44I

c.132C>A

1 paper

NM_024426.6

p.G43delFs

c.128delC

1 paper

NM_024426.6

p.G49V

c.146G>T