Varaico: Literature-Extracted Genetic Variants

WT1

1,404 papers

RefSeq Summary

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the norm...

Pfam Domains

WT1aa 1–321UCSCWilm's tumour protein

WT1aa 3–169UCSCWilm's tumour protein

WT1aa 74–377UCSCWilm's tumour protein

zf-C2H2aa 201–225UCSCZinc finger, C2H2 type

zf-C2H2aa 231–253UCSCZinc finger, C2H2 type

zf-C2H2aa 262–286UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

WT1 transcription factor

HGNC Previous Symbol

GUD

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

5 papers

NM_024426.6

p.G42G

c.126C>T

Surrounding Variants

1 paper

NM_024426.6

p.G43R

c.127G>C

1 paper

NM_024426.6

p.G42D

c.125G>A

1 paper

NM_024426.6

p.P41_G42del1

c.122_124delCCG

1 paper

NM_024426.6

p.G43A

c.128G>C

1 paper

NM_024426.6

p.G43delFs

c.128delC

1 paper

NM_024426.6

p.P41L

c.122C>T

1 paper

NM_024426.6

p.P41insFs

c.121_122insT

1 paper

NM_024426.6

p.D40D

c.120C>T

2 papers

NM_024426.6

p.I44I

c.132C>A

1 paper

NM_024426.6

p.W45_A46insFs

c.135_136insC

2 papers

NM_024426.6

p.W45*

c.135G>A

1 paper

NM_024426.6

p.R39P

c.116G>C