Varaico: Literature-Extracted Genetic Variants

WT1

1,404 papers

RefSeq Summary

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the norm...

Pfam Domains

WT1aa 1–321UCSCWilm's tumour protein

WT1aa 3–169UCSCWilm's tumour protein

WT1aa 74–377UCSCWilm's tumour protein

zf-C2H2aa 201–225UCSCZinc finger, C2H2 type

zf-C2H2aa 231–253UCSCZinc finger, C2H2 type

zf-C2H2aa 262–286UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

WT1 transcription factor

HGNC Previous Symbol

GUD

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_024426.6

p.L30L

c.90A>G

Surrounding Variants

1 paper

NM_024426.6

p.L30L

c.90A>C

1 paper

NM_024426.6

p.Q31*

c.91C>T

1 paper

NM_024426.6

p.Q31delFs

c.91delG

1 paper

NM_024426.6

p.Q31H

c.93G>T

1 paper

NM_024426.6

p.Q31H

c.93G>C

1 paper

NM_024426.6

p.Q31Q

c.93G>A

1 paper

NM_024426.6

p.C29*

c.87C>A

1 paper

NM_024426.6

p.C29delFs

c.86delC

2 papers

NM_024426.6

p.G28_C29del1

c.84_86delCAC

1 paper

NM_024426.6

p.C29delins

c.85delinsTCCC

1 paper

NM_024426.6

p.C29S

c.86G>C

1 paper

NM_024426.6

p.G28del1

c.82_83delCCC