Varaico: Literature-Extracted Genetic Variants

WT1

1,404 papers

RefSeq Summary

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the norm...

Pfam Domains

WT1aa 1–321UCSCWilm's tumour protein

WT1aa 3–169UCSCWilm's tumour protein

WT1aa 74–377UCSCWilm's tumour protein

zf-C2H2aa 201–225UCSCZinc finger, C2H2 type

zf-C2H2aa 231–253UCSCZinc finger, C2H2 type

zf-C2H2aa 262–286UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

WT1 transcription factor

HGNC Previous Symbol

GUD

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_024426.6

p.A18T

c.52G>A

Surrounding Variants

2 papers

NM_024426.6

p.A18E

c.53C>A

1 paper

NM_024426.6

p.P17S

c.49C>T

1 paper

NM_024426.6

p.Q20fs

c.58_59fs

1 paper

NM_024426.6

p.Q20insFs

c.58_59ins7

1 paper

NM_024426.6

p.S19_Q20delFs

c.57_58delGA

2 papers

NM_024426.6

p.A10_Q20delFs

c.29_59del31

2 papers

NM_024426.6

p.P15S

c.43C>T

1 paper

NM_024426.6

p.L5_V14del10

c.13_41del30

1 paper

NM_024426.6

p.V14_P15insFs

c.42_43insG

1 paper

NM_024426.6

p.H21R

c.62A>G

2 papers

NM_024426.6

p.V14D

c.41T>A

1 paper

NM_024426.6

p.H21insFs

c.62_63insA