Varaico: Literature-Extracted Genetic Variants

WT1

1,404 papers

RefSeq Summary

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the norm...

Pfam Domains

WT1aa 1–321UCSCWilm's tumour protein

WT1aa 3–169UCSCWilm's tumour protein

WT1aa 74–377UCSCWilm's tumour protein

zf-C2H2aa 201–225UCSCZinc finger, C2H2 type

zf-C2H2aa 231–253UCSCZinc finger, C2H2 type

zf-C2H2aa 262–286UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

WT1 transcription factor

HGNC Previous Symbol

GUD

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_024426.6

p.Q7*

c.19C>T

Surrounding Variants

1 paper

NM_024426.6

p.L6insFs

c.17dupT

1 paper

NM_024426.6

p.D2_L5delFs

c.5_14del10

1 paper

NM_024426.6

p.D8V

c.23A>T

1 paper

NM_024426.6

p.D8A

c.23A>C

1 paper

NM_024426.6

p.L5W

c.14T>G

1 paper

NM_024426.6

p.L4insFs

c.12dupC

1 paper

NM_024426.6

p.L5L

c.13T>C

1 paper

NM_024426.6

p.P9S

c.25C>T

1 paper

NM_024426.6

p.P9T

c.25C>A

1 paper

NM_024426.6

p.L4L

c.12C>T

1 paper

NM_024426.6

p.M1_D8del8

c.1_23del24

1 paper

NM_024426.6

p.L4insFs

c.11_12ins14