Varaico: Literature-Extracted Genetic Variants

XIAP

484 papers

RefSeq Summary

This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-...

Pfam Domains

BIRaa 29–94UCSCInhibitor of Apoptosis domain

BIRaa 166–231UCSCInhibitor of Apoptosis domain

BIRaa 268–331UCSCInhibitor of Apoptosis domain

UBA_BIRC2-3aa 369–420UCSCBIRC2/3-like, UBA domain

zf-C3HC4_3aa 446–490UCSCZinc finger, C3HC4 type (RING finger)

Gene Aliases

HGNC Name

X-linked inhibitor of apoptosis

HGNC Previous Symbols

API3; BIRC4

Papers

RefSeq ID

Protein change

DNA change

1–12 of 501 variants

25 papers

NM_001167.4

p.R381*

c.1141C>T

19 papers

NM_001167.4

p.Q423P

c.1268A>C

18 papers

NM_001167.4

p.R222*

c.664C>T

16 papers

NM_001167.4

p.R238*

c.712C>T

16 papers

NM_001167.4

p.G466*

c.1396G>T

14 papers

NM_001167.4

p.C203Y

c.608G>A

13 papers

NM_001167.4

p.G188E

c.563G>A

11 papers

NM_001167.4

p.E118*

c.352G>T

11 papers

NM_001167.4

p.A321G

c.962C>G

11 papers

NM_001167.4

p.N341delFs

c.1021_1022delAA

11 papers

NM_001167.4

p.T470S

c.1408A>T

11 papers

NM_001167.4

p.T470S

c.1409C>G