Varaico: Literature-Extracted Genetic Variants

XIAP

484 papers

RefSeq Summary

This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-...

Pfam Domains

BIRaa 29–94UCSCInhibitor of Apoptosis domain

BIRaa 166–231UCSCInhibitor of Apoptosis domain

BIRaa 268–331UCSCInhibitor of Apoptosis domain

UBA_BIRC2-3aa 369–420UCSCBIRC2/3-like, UBA domain

zf-C3HC4_3aa 446–490UCSCZinc finger, C3HC4 type (RING finger)

Gene Aliases

HGNC Name

X-linked inhibitor of apoptosis

HGNC Previous Symbols

API3; BIRC4

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_001167.4

p.A50T

c.148G>A

Surrounding Variants

1 paper

NM_001167.4

p.A50P

c.148G>C

2 papers

NM_001167.4

p.R49Q

c.146G>A

3 papers

NM_001167.4

p.R49*

c.145C>T

1 paper

NM_001167.4

p.G51R

c.151G>A

1 paper

NM_001167.4

p.G51R

c.151G>C

1 paper

NM_001167.4

p.L53P

c.158T>C

1 paper

NM_001167.4

p.T46K

c.137C>A

2 papers

NM_001167.4

p.T46insFs

c.137_138insT

2 papers

NM_001167.4

p.Y54C

c.161A>G

1 paper

NM_001167.4

p.T55_C63del9

c.163_188del27

1 paper

NM_001167.4

p.T55I

c.164C>T

1 paper

NM_001167.4

p.A44T

c.130G>A