Varaico: Literature-Extracted Genetic Variants

XIAP

484 papers

RefSeq Summary

This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-...

Pfam Domains

BIRaa 29–94UCSCInhibitor of Apoptosis domain

BIRaa 166–231UCSCInhibitor of Apoptosis domain

BIRaa 268–331UCSCInhibitor of Apoptosis domain

UBA_BIRC2-3aa 369–420UCSCBIRC2/3-like, UBA domain

zf-C3HC4_3aa 446–490UCSCZinc finger, C3HC4 type (RING finger)

Gene Aliases

HGNC Name

X-linked inhibitor of apoptosis

HGNC Previous Symbols

API3; BIRC4

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001167.4

p.N112_G113del2

c.334_338del6

Surrounding Variants

3 papers

NM_001167.4

p.Q111*

c.331C>T

1 paper

NM_001167.4

p.I110I

c.330C>A

1 paper

NM_001167.4

p.G113R

c.337G>C

1 paper

NM_001167.4

p.G113C

c.337G>T

1 paper

NM_001167.4

p.G113insFs

c.339dupT

2 papers

NM_001167.4

p.Q114*

c.340C>T

1 paper

NM_001167.4

p.G109fs

c.325_326fs

1 paper

NM_001167.4

p.Y115_K116insG

c.343_347ins3

1 paper

NM_001167.4

p.Y115C

c.344A>G

1 paper

NM_001167.4

p.Y115*

c.345C>A

1 paper

NM_001167.4

p.Y115*

c.345C>G

1 paper

NM_001167.4

p.N107S

c.320A>G