Varaico: Literature-Extracted Genetic Variants

XIAP

484 papers

RefSeq Summary

This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-...

Pfam Domains

BIRaa 29–94UCSCInhibitor of Apoptosis domain

BIRaa 166–231UCSCInhibitor of Apoptosis domain

BIRaa 268–331UCSCInhibitor of Apoptosis domain

UBA_BIRC2-3aa 369–420UCSCBIRC2/3-like, UBA domain

zf-C3HC4_3aa 446–490UCSCZinc finger, C3HC4 type (RING finger)

Gene Aliases

HGNC Name

X-linked inhibitor of apoptosis

HGNC Previous Symbols

API3; BIRC4

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

11 papers

NM_001167.4

p.E118*

c.352G>T

Surrounding Variants

1 paper

NM_001167.4

p.N119_Y120delFs

c.356_359del4

1 paper

NM_001167.4

p.V117_N119delins

c.350_356delinsATGC

1 paper

NM_001167.4

p.N119fs

c.355_356fs

1 paper

NM_001167.4

p.K116R

c.347A>G

1 paper

NM_001167.4

p.N119_Y120insFs

c.357_358insG

1 paper

NM_001167.4

p.Y120N

c.358T>A

1 paper

NM_001167.4

p.Y115*

c.345C>A

1 paper

NM_001167.4

p.Y115*

c.345C>G

1 paper

NM_001167.4

p.Y115C

c.344A>G

1 paper

NM_001167.4

p.Y115_K116insG

c.343_347ins3

2 papers

NM_001167.4

p.Q114*

c.340C>T

1 paper

NM_001167.4

p.G122E

c.365G>A