Varaico: Literature-Extracted Genetic Variants

XIAP

484 papers

RefSeq Summary

This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-...

Pfam Domains

BIRaa 29–94UCSCInhibitor of Apoptosis domain

BIRaa 166–231UCSCInhibitor of Apoptosis domain

BIRaa 268–331UCSCInhibitor of Apoptosis domain

UBA_BIRC2-3aa 369–420UCSCBIRC2/3-like, UBA domain

zf-C3HC4_3aa 446–490UCSCZinc finger, C3HC4 type (RING finger)

Gene Aliases

HGNC Name

X-linked inhibitor of apoptosis

HGNC Previous Symbols

API3; BIRC4

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001167.4

p.D130fs

c.388_389fs

Surrounding Variants

1 paper

NM_001167.4

p.D130fs

c.388_389fs

6 papers

NM_001167.4

p.L129_D130delFs

c.387_390del4

2 papers

NM_001167.4

p.L129fs

c.385_386fs

1 paper

NM_001167.4

p.R131_P132delFs

c.393_394delGC

1 paper

NM_001167.4

p.R131S

c.393G>C

1 paper

NM_001167.4

p.R131S

c.393G>T

1 paper

NM_001167.4

p.A128S

c.382G>T

1 paper

NM_001167.4

p.S133F

c.398C>T

1 paper

NM_001167.4

p.H136ins2

c.407_408ins6

2 papers

NM_001167.4

p.S123N

c.368G>A

1 paper

NM_001167.4

p.S123I

c.368G>T

2 papers

NM_001167.4

p.A137_D138insT

c.409_413ins3