Varaico: Literature-Extracted Genetic Variants

XIAP

484 papers

RefSeq Summary

This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-...

Pfam Domains

BIRaa 29–94UCSCInhibitor of Apoptosis domain

BIRaa 166–231UCSCInhibitor of Apoptosis domain

BIRaa 268–331UCSCInhibitor of Apoptosis domain

UBA_BIRC2-3aa 369–420UCSCBIRC2/3-like, UBA domain

zf-C3HC4_3aa 446–490UCSCZinc finger, C3HC4 type (RING finger)

Gene Aliases

HGNC Name

X-linked inhibitor of apoptosis

HGNC Previous Symbols

API3; BIRC4

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001167.4

p.Y161N

c.481T>A

Surrounding Variants

1 paper

NM_001167.4

p.Y161D

c.481T>G

1 paper

NM_001167.4

p.Y161S

c.482A>C

2 papers

NM_001167.4

p.Y161C

c.482A>G

1 paper

NM_001167.4

p.N157S

c.470A>G

1 paper

NM_001167.4

p.A165S

c.493G>T

1 paper

NM_001167.4

p.A165_R166delins

c.495_496delinsAT

3 papers

NM_001167.4

p.R166K

c.497G>A

5 papers

NM_001167.4

p.R166I

c.497G>T

1 paper

NM_001167.4

p.P155Q

c.464C>A

2 papers

NM_001167.4

p.L167*

c.500T>A

2 papers

NM_001167.4

p.L167*

c.500T>G

1 paper

NM_001167.4

p.K168delFs

c.503delA